Research
Cell Cycle Using Bioinformatics Approaches
Ear Tissue
Regenerative Capacity
Wild Type Mice
Developmental Biology
Valuable Research Model
Growth Factor Delivery Mechanisms
Regenerative Medicine
Present Evidence
Current Methods
Structural Gaps
Marked Clinical Advance
Fold Change
Quantitative Proteomic Analysis, Quantitative Proteomics Analysis
System Biology Approach, Systems Biology Approach
Adult Stem Cells
Extracellular Matrix Degradation
Embryonic Stem Cells, Embryonic Stem Cell
Long Bone, Long Bones
American Association
Developmental Dynamics
Bone Marrow Cells
New Approach, New Approaches
Control Frogs
St Century
Growth Stages
Schwann Cells
Bone Regeneration
Stem Cell Markers
Adult Somatic Cells
Competent Cells
Previous Study, Previous Studies
Molecular Basis
Dedifferentiated Cells
Cell Protection
Unique Proteins
General Value
Special Interest
Quantitative Label
Complex Structures
High Levels
Biological Process Categories
Several Mechanisms
Unfolded Protein Response
Cell Division Control
Transcription Factor Analysis
Past Century
Digit Stages
Major Questions
Central Role, Central Roles
Time Points
Inductive Agent
Skeletal Defect
Bone Formation
Tissue Breakdown
Nerve Dependency
Gland Cells
Silico Methodology
Peripheral Nerves, Peripheral Nerve
Month Samples
Time Span
Experimental Methods
Critical Mass
Tissue Engineering Research
Antibody Array
Clinical Means
Molecular Entities
Nerve Independent
Fracture Repair
Tissue Inhibitors, Tissue Inhibitor
Tissues Organs, Tissue Organization
Xenopus Model System
Regenerative Powers
Many Unanswered Questions
Blood Vessels, Blood Vessel
Normal Skeletal Parts
Bearing Model
Target Genes, Targets Genes
Protein Expression
Two Cell Sources
P P Interactions
Genome Sequence Based Bioinformatics Tools
M Phase Initiation
New Tissue
Fibroblast Growth Factor
Cell Transplantation, Cell Transplants
Spinal Cord Regeneration
Protein Protein
Interacting Proteins
Protein Interactions
Biomedical Literature
Regenerative Biology
Molecular Biology
Lesioned Spinal Cord
Central Nervous System
Bone Marrow Stem Cells
Injury Environment
Culture Techniques
Insufficient Data
Resident Stem Cells
Artificial Tissues
Heart Muscle
Cns Tissue
Cardiac Regeneration
Tissue Specific Regeneration
Contemporary Evidence
Fibrotic Response
Non Regenerating Mammalian Tissues
Damaged Tissues
Tissue Engineered Medical Products Standards
Molecular Events
Positional Identity, Positional Identities
Major Role
Unique Similarities
Four Topics
Epigenetic Reprogramming
Evolutionary Principles
Research Team
Current Performance
Third Topic
Biological Relevance
Widely Used Yeast
Large Quantities, Large Quantity
Controlling Expression
Network Analysis
Unique Process
Pluripotent Escs
Regeneration Science
Laboratory Experiments
Chemical Induction
Tgf Beta
Protein Kinase Complex
Biological Cells
Gene Activation, Gene Activity
Complex Biological Process
Pathway Analysis
Human Tissues, Human Tissue
Glial Growth Factor
Many Tissues
Neural Stem Cell Behavior
Neural Injury
Epidermal Growth Factor
Cell Surface
Progenitor Cells
Normal Development
Wound Site
Cellular Plasticity
Mature Cells
Basic Research Issues
Tissue Restoration
Non Regenerating Tissues
Multiple Cell Types
Limb Development
Solid Organ Transplantation, Solid Organ Transplants
Current Understanding
Self Organizing System
Trophic Factors
Neural Retina
Life Cycle
Local Cell Interactions
Positional Information
Cell Biology
Cell Cell Adhesion, Cell Cell Adhesivity
Muscle Cells
Powerful Biological Tools
Jump Start
Tissue Damage
Clinical Treatment, Clinical Treatments
Biological Function, Biologic Functions, Biological Functions
Significant Avenue
Human Cells
Original Structural Pattern
Degenerative Disease
Nuclear Receptors
Economic Production, Economic Productivity
Transduction Pathways
Premature Death
Health Care Costs
Proliferation Factor, Proliferation Factors
Better Health
Cell Cell Signaling Network
Bioinformatic Analyses
Physical Signals
Molecular Promoters
Regeneration Deficient Tissues
Many Non
Systematic Investigations
Suspected Survival
Different Responses, Different Response
Related Processes
Molecular Composition
Developing Tissue
Existing Table
Key Role, Key Roles
Staging Series
Functional Reconstruction
New Neurons
Gap Replacement
Three Approaches
Retinoic Acid
Three Mechanisms
Different Kinds, Different Kind
Tissue Structures, Tissue Structure
Drug Delivery System, Drug Delivery Systems
Damaged Area
Substantial Evidence
Regenerative Mechanisms
Organ Replacement
Biomaterial Scaffold
Seeding Cells
Appropriate Signaling Environment
Two Features
Important Regulator
Wound Repair
Repair Society
Immune System
Growth Potential
Environmental Stressors
Two Way, Two Ways
Pluripotent Cells
Control Group
Developmental Potency
Normal Fate
Regulatory Approval
Natural Capability
Third Strategy
Pilot Study
Three Major Factors
Ultraviolet Light
Wide Range, Wide Ranges
Six Percent
Site Specific Tissue
Developmental Plasticity
Central Feature
Many Adult Tissues
Sodium Channels
Molecular Analysis
Specific Malformations
Environmental Chemicals
Tissue Lineages
Developmental Events
Municipal Water
Clinical Reality
Recent Progress
Pond Water
Increasing Levels, Increased Levels
Necessary Intersection
Large Proportion
Natural Downregulation
Differentiation Program
Diabetic Symptoms
Large Gaps
Bioartificial Pancreas
Remarkable Advances
Replacement Parts
Adult Rat, Adult Rats
Islet Cells
Articular Cartilage
Failing Tissues
Positional Memory, Positional Memories
Three Basic Research Approaches
Pattern Completion
Regenerative Failure
Pd Axis
Ra Treatment
Ten Days
Lower Doses
Three Concepts
Regulatory Molecules
Molecular Mechanisms, Molecular Mechanism, Molecular Mechanics
Molecular Characteristics
Intracellular Signaling Systems
Developmental Roles
Vivo Substitutes
Experimental Evidence
One Stage
Patterning Genes
Protein Products
Conceptual Framework
Several Approaches
Non Uniformity
Pattern Formation
Muscle Pattern
Position Related Differences
Missing Structures
Cellular Basis
Molecular Property
Days Later
Initial Positional Value
Corresponding Levels
Skeletal Patterns
Sixty Percent
Regenerating Extremity
Modulating Transcription
Small Animals
Spatial Organization
Eight Cases
Pattern Regulation
Transplantation Experiments
New Structure, New Structures
Experimental Regenerates
Cellular Interactions
Large Animals
Single Limbs
Scanning Laser
One Approach
Early Stages, Early Stage
Vivo Assay
Experimental Zoology
Level Specific Properties
Specific Variation, Specific Variations
Cellular Mechanisms, Cellular Mechanism
Stage Dependent Shift
Level Specific Differences
Cellular Recognition System
Various Stages
Different Means
Following Types
Two Digits
One Direction
Visual Image
Growth Curves
Histochemistry Society
Four Groups
Maximum Extent
Mechanical Properties
Host Tissues
Donor Tissues
Vast Majority
Species Specific Size Differences
Two Categories
Reversal Experiments
Limb Area
Normal Number
Previous Claims
Graft Tissue
Regeneration Field
Neutral Location
Regenerating Organ
Cross Section
Prospective Significance
Limb Cell Phenotype
Substantial Number
Vitro Experiments
Biological Diversity
Varying Doses
Mesenchymal Cells
Molecular Studies
Extra Digits
Future Understanding
Detailed Review
List of Publications (67)
In 2013
In 2011
65
Matrix metalloproteinase expression during blastema formation in regeneration-competent versus regeneration-deficient amphibian limbs.
Found on Publication Page
64
Xenopus laevis as a novel model to study long bone critical-size defect repair by growth factor-mediated regeneration.
Found on Publication Page
In 2010
In 2009
In 2008
57
Discovering implicit protein-protein interactions in the cell cycle using bioinformatics approaches.
Found on Publication Page
In 2007
In 2005
In 2004
In 2003
In 2002
In 2001
46
Leaping lopsided: a review of the current hypotheses regarding etiologies of limb malformations in frogs.
Found on Publication Page
44
ASTM lights the way for tissue engineered medical products standards: jump start for combination medical products that restore biological function of human tissues.
Found on Publication Page
In 2000
43
Frog limb deformities: an "eco-devo" riddle wrapped in multiple hypotheses surrounded by insufficient data.
Found on Publication Page
In 1999
In 1998
In 1997
In 1996
In 1993
35
Asymmetric effects of retinoic acid on pattern formation in the transverse axes of regenerating axolotl limbs: test of a hypothesis.
Found on Publication Page
In 1992
32
Retinoic acid-induced change in anteroposterior positional identity in regenerating axolotl limbs is dose-dependent.
Found on Publication Page
In 1991
In 1990
28
The effect of retinoic acid on positional memory in the dorsoventral axis of regenerating axolotl limbs.
Found on Publication Page
In 1988
27
Cellular retinoic acid binding protein: detection and quantitation in regenerating axolotl limbs.
Found on Publication Page
26
Retinoic acid coordinately proximalizes regenerate pattern and blastema differential affinity in axolotl limbs.
Found on Publication Page
25
Retinoic acid proximalizes level-specific properties responsible for intercalary regeneration in axolotl limbs.
Found on Publication Page
In 1987
24
Use of retinoids to analyze the cellular basis of positional memory in regenerating amphibian limbs.
Found on Publication Page
In 1986
23
Retinoic acid modifies positional memory in the anteroposterior axis of regenerating axolotl limbs.
Found on Publication Page
In 1984
19
The urodele limb regeneration blastema. Determination and organization of the morphogenetic field.
Found on Publication Page
In 1983
In 1982
In 1981
In 1980
In 1979
12
Development of the tibiotarsus in the chick embryo: biosynthetic activities of histologically distinct regions.
Found on Publication Page
In 1978
In 1977
9
Self-organizational capacity of distally transplanted limb regeneration blastemas in larval salamanders.
Found on Publication Page
In 1975
7
Regulation after proximal or distal transposition of limb regeneration blastemas and determination of the proximal boundary of the regenerate.
Found on Publication Page
In 1974
6
Denervation-induced changes in soluble protein content during forelimb regeneration in the adult newt, Notophthalmus viridescens.
Found on Publication Page
In 1972
5
Relative rates of protein synthesis and reaggregation in embryonic chick liver cells cultured in defined and supplemented media.
Found on Publication Page
In 1971
In 1968
3
The urodele limb regeneration blastema: a self-organizing system. I. Morphogenesis and differentiation of autografted whole and fractional blastemas.
Found on Publication Page
In 1966
1
The effects of thiourea and cortisone acetate on duodenal length and diameter and on morphogenesis of duodenal villi in chick embryos.
Found on Publication Page