Jennifer Fiegel

Profile Picture of Jennifer Fiegel
Title
Associate Professor
Department
Chemical and Biochemical Engineering
Institution
University of Iowa

Education

  • Ph.D., Chemical and Biomolecular Engineering, The Johns Hopkins University, 2004.
  • B.S. Chemical Engineering, University of Massachusetts at Amherst, 1998.

Research Interests

Pulmonary Drug Delivery   International Society   Biophysics of Lung Fluids  

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Biography

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Homepages

Contact Information

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Research
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List of Publications (74)
In 2016
74

Calf lung surfactant recovers surface functionality after exposure to aerosols containing polymeric particles. AM Farnoud, J Fiegel Journal of aerosol medicine and pulmonary drug delivery 29 (1), 10-23, 2016.

Found on Publication Page
73

Large porous hollow particles: lightweight champions of pulmonary drug delivery. S Gharse, J Fiegel Current pharmaceutical design 22 (17), 2463-2469, 2016.

Found on Publication Page
72

Tensiometric and Phase Domain Behavior of Lung Surfactant on Mucus-like Viscoelastic Hydrogels. DM Schenck, J Fiegel ACS applied materials & interfaces 8 (9), 5917-5928, 2016.

Found on Publication Page
In 2015
71

Abstracts: International Society for Aerosols in Medicine eV 20th ISAM Congress Munich Holiday Inn-City Center, Germany May 30June 3, 2015. RK Wolff, N Heuz-Vourc'h, H Virginie, N Rabbe, L Guilleminault, F Paul, ... Journal of Aerosol Medicine and Pulmonary Drug Delivery 28 (3), A-1-A-43, 2015.

Found on Publication Page
70

Spectrophotometric evaluation of potassium nitrate penetration into the pulp cavity. SR Kwon, DV Dawson, DM Schenck, J Fiegel, PW Wertz Operative dentistry 40 (6), 614-621, 2015.

Found on Publication Page
In 2014
69

Quantification of confocal images of biofilms grown on irregular surfaces. SS Ross, MH Tu, ML Falsetta, MR Ketterer, MR Kiedrowski, AR Horswill, ... Journal of microbiological methods 100, 111-120, 2014.

Found on Publication Page
68

Synthetic tracheal mucus with native rheological and surface tension properties. R Hamed, J Fiegel Journal of biomedical materials research Part A 102 (6), 1788-1798, 2014.

Found on Publication Page
67

Particles for treatment of pulmonary infection. DA Edwards, J Fiegel, J Sung US Patent 8,846,607, 2014.

Found on Publication Page
66

Particles for treatment of pulmonary infection. DA Edwards, J Fiegel, J Sung US Patent 8,846,607, 2014.

Found on Publication Page
65

Particles for treatment of pulmonary infection. DA Edwards, J Fiegel, J Sung US Patent 8,846,607, 2014.

Found on Publication Page
In 2013
64

Surfactant Interactions with Sub-Micron Particles: The Importance of Route of Exposure. AM Farnoud, J Fiegel Journal of Aerosol Medicine and Pulmonary Drug Delivery 26 (2), A60-A61, 2013.

Found on Publication Page
63

DEVELOPMENT OF ERYTHROMYCIN-LOADED PLGA NANOPARTICLES FOR TARGETED DELIVERY TO THE LUNG EPITHELIUM. MH Tu, MA Apicella, J Fiegel JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 26 (2), A43-A43, 2013.

Found on Publication Page
62

Abstracts: International Society for Aerosols in Medicine 19th International Congress Chapel Hill, North Carolina, USA April 610, 2013. SM Rowe, SD Davis, WM Abraham, JR Sabater, T Ahmed, CJ Roy, ... Journal of Aerosol Medicine and Pulmonary Drug Delivery 26 (2), A-1-A-69, 2013.

Found on Publication Page
61

DISPERSION COMPOUNDS ENHANCE ANTIBIOTIC EFFECTIVENESS AGAINST PSEUDOMONAS AERUGINOSA BIOFILMS. SS Ross, J Fiegel JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 26 (2), A29-A30, 2013.

Found on Publication Page
60

Synthesis, surface properties, and biocompatibility of 1, 2, 3-triazole-containing alkyl -D-xylopyranoside surfactants. ED Oldham, S Seelam, C Lema, RJ Aguilera, J Fiegel, SE Rankin, ... Carbohydrate research 379, 68-77, 2013.

Found on Publication Page
59

Interaction of dipalmitoyl phosphatidylcholine monolayers with a particle-laden subphase. AM Farnoud, J Fiegel The Journal of Physical Chemistry B 117 (40), 12124-12134, 2013.

Found on Publication Page
In 2012
58

Enhanced analysis of bacteria susceptibility in connected biofilms. SS Ross, JM Reinhardt, J Fiegel Journal of microbiological methods 90 (1), 9-14, 2012.

Found on Publication Page
57

Disruption of phosphatidylcholine monolayers and bilayers by perfluorobutane sulfonate. ED Oldham, W Xie, AM Farnoud, J Fiegel, HJ Lehmler The Journal of Physical Chemistry B 116 (33), 9999-10007, 2012.

Found on Publication Page
56

Synthesis and characterization of triazole-containing alkyl xyloside surfactants. ED Oldham, S Seelam, CF Lema, RJ Aguilera, J Fiegel, SE Rankin, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012.

Found on Publication Page
55

Disruption of phosphatidylcholine lipid assemblies by perfluorobutanesulfonate. ED Oldham, W Xie, AM Farnoud, J Fiegel, HJ Lehmler ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012.

Found on Publication Page
54

Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. SS Ross, J Fiegel International journal of antimicrobial agents 40 (2), 177-181, 2012.

Found on Publication Page
53

Low concentrations of negatively charged sub-micron particles alter the microstructure of DPPC at the airwater interface. AM Farnoud, J Fiegel Colloids and Surfaces A: Physicochemical and Engineering Aspects 415, 320-327, 2012.

Found on Publication Page
In 2011
52

Controlled transport for pulmonary drug delivery. J Fiegel, T Brenza, R Hamed Controlled pulmonary drug delivery, 143-163, 2011.

Found on Publication Page
51

Discussion of Water Content in Spray-Dried Powders. A Kock, L Sanchez, S Ross, J Fiegel .

Found on Publication Page
In 2010
50

Optimization of Spray Dry Parameters for Anti-Biofilm Treatments. A Kock, S Ross, J Fiegel .

Found on Publication Page
49

The particle has landedcharacterizing the fate of inhaled pharmaceuticals. JS Patton, JD Brain, LA Davies, J Fiegel, M Gumbleton, KJ Kim, ... Journal of Aerosol Medicine and Pulmonary Drug Delivery 23 (S2), S-71-S-87, 2010.

Found on Publication Page
In 2009
48

Designing Nanotechnology for the Lungs, University of Iowa, Nano REU Summer Program, Jul 23, 2009.

Found on CV
47

Nanotechnology, University of Iowa, Environmental Health and Safety, Jun 19, 2009.

Found on CV
46

Therapeutic Design and Toxicity of Inhalable Nanoparticulate Aerosols, University of Iowa, Department of Occupational and Environmental Health - Toxicology Research Seminar Series, Dec 4, 2009.

Found on CV
45

Therapeutic Aerosols to Treat Respiratory Infections: From Biofilms to Mucosal Fluid Interactions, University of Iowa, Department of Mechanical and Industrial Engineering, Feb 26, 2009.

Found on CV
44

The Particle Has Landed - Mucus, Surfactant and Lining Fluid Interactions, 1000 Years of Pharmaceutical Aerosols Conference, Reykjavik, Iceland, Oct 2, 2009.

Found on CV
In 2008
43

J. Fiegel, L. Garcia-Contreras, M. Thomas, J. Verberkmoes, A. Hickey, D. Edwards. Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. Pharm. Res. 2008; 25(4): 805-811.

Found on CV
42

Development of a Dry Powder Aerosol for the Dispersion and Eradication of Respiratory Biofilms. E Thomas, B Stohs, J Fiegel Proceedings of the American Institute of Chemical Engineers, 2008.

Found on Publication Page
41

Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. J Fiegel, L Garcia-Contreras, M Thomas, J VerBerkmoes, K Elbert, ... Pharmaceutical research 25 (4), 805-811, 2008.

Found on Publication Page
40

Particulate aerosols for the treatment of respiratory infections, Particles 2008 Conference, Orlando, FL, May 2008.

Found on CV
39

Exhaled Bioaerosol Formation: Toward New Strategies to Reduce Airborne Infectious Disease Transmission, University of Iowa, Department of Chemistry - Physical and Environmental Chemistry Seminar Series, May 5, 2008.

Found on CV
In 2007
38

L. Garcia-Contreras, J. Fiegel, M.J. Telko, K. Elbert, A. Hawi, M. Thomas, J. VerBerkmoes, W.A. Germishuizen, P.B. Fourie, A.J. Hickey, D. Edwards. Inhaled large porous particles of Curriculum Vitae - Jennifer Fiegel capreomycin for the treatment of tuberculosis in a guinea pig model. Antimicrob. Agents Chemother. 2007; 51(8): 2830-2836.

Found on CV
37

Novel Aerosols for Treating Tuberculosis, University of Iowa, College of Medicine: Pulmonary Conference, Mar 26, 2007.

Found on CV
36

Advances in Aerosol Delivery, IUPAC/OPCW Workshop: Impact of Scientific Developments on the Chemical Weapons Convention (International Union of Pure and Applied Chemistry/Organisation for the Prohibition of Chemical Weapons), Zagreb, Croatia, Apr 24, 2007.

Found on CV
35

W. Watanabe, M. Thomas, R. Clarke, A. Klibanov, R. Langer, G. Fuller, L. Griel, J. Fiegel, D. Edwards. Why inhaling salt water changes what we exhale. J. Colloid Interface Sci. 2007; 307(1): 71-78.

Found on CV
34

Biodegradable polymer compositions, compositions and uses related thereto. J Hanes, J Fu, J Fiegel US Patent 7,163,697, 2007.

Found on Publication Page
33

Biodegradable polymer compositions, compositions and uses related thereto. J Hanes, J Fu, J Fiegel US Patent 7,163,697, 2007.

Found on Publication Page
32

Why inhaling salt water changes what we exhale. W Watanabe, M Thomas, R Clarke, AM Klibanov, R Langer, J Katstra, ... Journal of colloid and interface science 307 (1), 71-78, 2007.

Found on Publication Page
31

Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model. L Garcia-Contreras, J Fiegel, MJ Telko, K Elbert, A Hawi, M Thomas, ... Antimicrobial agents and chemotherapy 51 (8), 2830-2836, 2007.

Found on Publication Page
30

Treating Tuberculosis via Inhaled Antibiotics, University of Iowa, Department of Chemistry - Analytical Chemistry Seminar Series, Apr 19, 2007.

Found on CV
In 2006
29

Engineering Novel Medical Aerosols: From the Bench to the Clinic, University of Iowa, Department of Chemical and Biochemical Engineering, Oct 12, 2006.

Found on CV
28

Airborne infectious disease and the suppression of pulmonary bioaerosols. J Fiegel, R Clarke, DA Edwards Drug discovery today 11 (1), 51-57, 2006.

Found on Publication Page
27

J. Fiegel, R. Clarke, D. Edwards. Airborne infectious disease and the suppression of exhaled aerosols [review]. Drug Discovery Today. 2006; 11(1-2):51-57.

Found on CV
In 2005
26

Dry Powder Aerosols for Therapeutic Drug Delivery. J Fiegel The 2005 Annual Meeting, 2005.

Found on Publication Page
25

Controlling the Production of Exhaled Bioaerosols. J Fiegel, W Wanatabe, GG Fuller, D Edwards Proceedings of the American Institute of Chemical Engineers, 2005.

Found on Publication Page
24

Wetting of a particle in a thin film. J Fiegel, F Jin, J Hanes, K Stebe Journal of colloid and interface science 291 (2), 507-514, 2005.

Found on Publication Page
23

Dry powder aerosols for multi-drug resistant tuberculosis (Mdr-Tb) treatment. J Fiegel, L Garcia-Contreras, K Elbert, A Hickey, D Edwards 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, 2005.

Found on Publication Page
In 2004
22

J. Fiegel, J. Fu, J. Hanes. Poly(ether-anhydride) microparticle aerosolization improved by controlling particle surface properties. J. Control. Release. 2004; 96(3):411-423.

Found on CV
21

Biodegradable polymeric nanoparticles for drug delivery. Applications for Nanoparticle Design and Microfabrication in Protein and Peptide Delivery Workshop: 3rd Annual Protein and Peptide Formulation Strategies, Sponsored by the Institute for International Research, San Francisco, CA, Mar 2004.

Found on CV
20

Synthesis and characterization of PEG-based ether-anhydride terpolymers: novel polymers for controlled drug delivery. J Fu, J Fiegel, J Hanes Macromolecules 37 (19), 7174-7180, 2004.

Found on Publication Page
19

Poly (ether-anhydride) dry powder aerosols for sustained drug delivery in the lungs. J Fiegel, J Fu, J Hanes Journal of controlled release 96 (3), 411-423, 2004.

Found on Publication Page
18

Poly (ether-anhydride) Dry Particle Aerosols. J Fiegel Johns Hopkins University, 2004.

Found on Publication Page
17

Gene delivery to the lung. J Hanes, M Dawson, Y Har-el, J Suh, J Fiegel Drugs and the Pharmaceutical Sciences 134, 489-540, 2004.

Found on Publication Page
16

J. Fiegel, J. Fu, J. Hanes. Poly(ether-anhydride) microparticle aerosolization improved by controlling particle surface properties. J. Control Release. 2004; 96 (3) 411-423

Found on Publication Text
15

J. Fu, J. Fiegel, J. Hanes. Synthesis and characterization of PEG-based ether-anhydride terpolymers: Novel polymers for pulmonary drug delivery. Macromolecules; 2004. 37(19): 7174- 7180.

Found on CV
In 2003
14

Large porous particle impingement on lung epithelial cell monolayerstoward improved particle characterization in the lung. J Fiegel, C Ehrhardt, UF Schaefer, CM Lehr, J Hanes Pharmaceutical research 20 (5), 788-796, 2003.

Found on Publication Page
13

BIODEGRADABLE POLYMER COOMPOSITIONS. J HANES, J FU, J FIEGEL WO Patent 2,003,000,237, 2003.

Found on Publication Page
12

J. Hanes, M. Dawson, Y. Har-el, J. Suh, and J. Fiegel. Gene Therapy in the Lung. In: A. J. Hickey (ed.) Pharmaceutical Inhalation Aerosol Technology, 2nd edition. Vol. 134. New York: Marcel Dekker Inc. 2003.

Found on CV
In 2002
11

C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, C.-M. Lehr. Drug absorption by the respiratory mucosa - Cell culture models and particulate drug carriers. J. Aerosol Med. 2002; 15(2):131-139.

Found on CV
10

New polymeric carriers for controlled drug delivery following inhalation or injection. J Fu, J Fiegel, E Krauland, J Hanes Biomaterials 23 (22), 4425-4433, 2002.

Found on Publication Page
9

Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers. C Ehrhardt, J Fiegel, S Fuchs, R Abu-Dahab, UF Schaefer, J Hanes, ... Journal of aerosol medicine 15 (2), 131-139, 2002.

Found on Publication Page
8

Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies. C Ehrhardt, C Kneuer, J Fiegel, J Hanes, U Schaefer, KJ Kim, CM Lehr Cell and tissue research 308 (3), 391-400, 2002.

Found on Publication Page
7

Cell & Tissue Research 2002; 308:391-400.

Found on CV
Unspecified
6

J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.-M. Lehr, J. Hanes. Large porous particle impingement on lung epithelial cell monolayers: Toward improved particle characterization in the lung. Pharm. Res.

Found on CV
5

J.S. Patton, J.D. Brain, L.A. Davies, J. Fiegel, M. Gumbleton, K.-J. Kim, M. Sakagami, R. Vanbever, C. Ehrhardt. The particle has landed - Characterizing the fate of inhaled pharmaceuticals. J. Aerosol Med. Pulm. Drug Deliv. Submitted.

Found on CV
4

J. Fu, J. Fiegel, E. Krauland, J. Hanes. New polymer carriers for pulmonary drug delivery.

Found on CV
3

J. Fiegel, F. Jin, J. Hanes, K. Stebe. Wetting of a particle in a thin film. J. Colloid Interface Sci.

Found on CV
2

C. Ehrhardt, C. Kneuer, J. Fiegel, J. Hanes, U.F. Schaefer, K.-J. Kim, C.-M. Lehr. Influence of apical fluid volume on the development of functional cellular junctions in the human bronchial epithelial cell line 16HBE14o-: implications for the use as an in vitro model for drug absorption.

Found on CV
1

T. Brenza, R. Hamed, and J. Fiegel. Controlled transport for pulmonary drug delivery. In: H. Smyth and A. Hickey (eds.) Controlled Release Science and Technology: Pulmonary Delivery.

Found on CV
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