Juliana Quay

Title

Graduate Student (Ph.D. Candidate)

Department

Department of Molecular Physiology and Biophysics

Institution

Vanderbilt University

juliana.quay@vanderbilt.edu

Education

B.S. Chemistry

Research Interests

Biochemistry Neuronal Signaling Neuroscience

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Biography

I am interested in research with clinical/translational applications at the interface of biochemistry and neuroscience. My undergraduate training involved four years of work in Jason Hurlbert's structural biology laboratory at Winthrop University, where I worked on the expression, purification, and crystallization of a novel calcium-binding protein, and a summer assistantship in Guoping Feng's molecular neuroscience laboratory, where I worked to map thalamic circuits in mouse models of neuropsychiatric disease. I earned my B.S. in chemistry with a concentration in biochemistry from Winthrop University in May 2020. I am currently a Ph.D. candidate in the Vanderbilt University Chemical and Physical Biology program. I work in Dr. Roger Colbran's laboratory, where I am working to elucidate the mechanisms of interaction between CaMKII, a mediator of calcium signaling, and its associated proteins (CaMKAPs). I am probing these interactions using CaMKII variants that are linked to human neurodevelopmental disorders. The mechanisms of CaMKII-CaMKAP interactions and the biochemical consequences of these human variants are not well-characterized. My studies will further inform us on these issues, and will provide insight on the role of CaMKII and CaMKAPs in the molecular basis of disease.

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Contact Information

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Research

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Cloud List

List of Publications (7)

In 2023

Clustering of CaV1.3 L type calcium channels by Shank3 (2023)
Found on Publication Page

In 2022

Clustering of CaV1.3 L-type calcium channels by Shank3 (2022)
Found on Publication Page

Elucidating the Mechanisms of CaMKII-CaMKAP Interactions (2022)
Found on Publication Page

In 2021

Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. (2021)
Found on Publication Page

Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis-projecting mossy cells in the mouse dentate gyrus. (2021)
Found on Publication Page

In 2020

Characterization of EfhX, a calcium sensor protein in Xanthomonas required for elicitation of the hypersensitive response in Solanum species (2020)
Found on Publication Page

In 2018

Expression and Purification of a Novel Calcium Binding Protein Necessary for Phytopathogenesis in Xanthomonas strain (2018)
Found on Publication Page

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Colleagues

Oleg Tutanov

Vanderbilt University

Ashlynn Sherwood

Vanderbilt University

Aishwarya Venkataravi

Vanderbilt University

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