Research
Neurotrophic Factor, Neurotrophic Factors
Mouse Model, Mouse Models
Ag Metabolism
Transgenic Mice
Behavioral Changes
Neurological Health
Neurodevelopmental Role
Spatial Learning
Memory Consolidation
Adult Mice
Adolescent Trauma
Temporal Association
Posttraumatic Stress Disorder
Fear Memories, Fear Memory
Adult Neurogenesis
Motor Learning
Early Life Stress
Food Intake
White Dm
Memory Function
Superior Learning
Motor Training
Genetic Approaches
Environmental Enrichment
Reduced Clearance
Synaptic Dysfunction
Inducible Protein Knockout
Amyloid Deposition
Temporal Requirements, Temporal Requirement
Genetic Studies
Genetic Enhancement
Synaptic Plasticity
Transgenic Overexpression
Structural Changes
Continuous Infusion
Memory Deficits
Crucial Process
Traumatic Brain Injury
Spatiotemporal Expression
Gene Expression
Beta Amyloid
Nmda Receptors, Nmda Receptor
Dopaminergic Neuronal System
Mouse Brain
Memory Impairments
Synergistic Interaction
Cognitive Enhancer
Mrna Expression
List of Publications (49)
In 2014
49
Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease.. Jian Zhang, Mei Hu, Zhaoqian Teng, Ya-Ping Tang, Chu Chen
Found on Publication Page
In 2013
48
Delta(9)-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling. Rongqing Chen, Jian Zhang, Ni Fan, Zhao-Qian Teng, Yan Wu, Hongwei Yang, Ya-Ping Tang, Hao Sun, Yunping Song, Chu Chen
Found on Publication Page
47
Temporal association of elevated cholecystokininergic tone and adolescent trauma is critical for posttraumatic stress disorder-like behavior in adult mice. Anu Joseph, Mingxi Tang, Takayoshi Mamiya, Qian Chen, Ling-Ling Yang, Jianwei Jiao, Na Yu, Ya-Ping Tang
Found on Publication Page
46
Expression of the G72/G30 gene in transgenic mice induces behavioral changes.. L Cheng, E Hattori, A Nakajima, N S Woehrle, M D Opal, C Zhang, K Grennan, S C Dulawa, Y-P Tang, E S Gershon, C Liu
Found on Publication Page
In 2012
45
Neurodevelopmental Role for VGLUT2 in Pyramidal Neuron Plasticity, Dendritic Refinement, and in Spatial Learning. Hongbo He, Amanda H Mahnke, Sukhjeevan Doyle, Ni Fan, Chih-Chieh Wang, Benjamin J Hall, Ya-Ping Tang, Fiona M Inglis, Chu Chen, Jeffrey D Erickson
Found on Publication Page
44
Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease. Rongqing Chen, Jian Zhang, Yan Wu, Dongqing Wang, Guoping Feng, Ya-Ping Tang, Zhaoqian Teng, Chu Chen
Found on Publication Page
43
Tang MX, Joseph A, Tang YP (2012) Interaction between CCKergic system and hypothalamus-pituitary-adrenal axis system in response to early-life stress. Glucocorticoids (book chapter) 21-40.
Found on Publication Text
In 2011
42
Sun XY, Hayashi Y, Xu S, Kanou Y, Takagishi Y, Tang YP, Murata Y (2011) Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake. PLoS ONE 6: e-14605.
Found on Publication Text
In 2010
41
Bi-Directional Effect of Cholecystokinin Receptor-2 Overexpression on Stress-Triggered Fear Memory and Anxiety in the Mouse. Qian Chen, Mingxi Tang, Takayoshi Mamiya, Heh-In Im, Xiaoli Xiong, Anu Joseph, Ya-Ping Tang
Found on Publication Page
40
TNF- and Microglial Hormetic Involvement in Neurological Health & Migraine.. Richard P Kraig, Heidi M Mitchell, Barbara Christie-Pope, Phillip E Kunkler, David M White, Ya-Ping Tang, George Langan
Found on Publication Page
In 2009
39
Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation. Heh-In Im, Akira Nakajima, Bo Gong, Xiaoli Xiong, Takayoshi Mamiya, Elliot S Gershon, Min Zhuo, Ya-Ping Tang
Found on Publication Page
In 2008
38
Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse. Qian Chen, Akira Nakajima, Se Hoon Choi, Xiaoli Xiong, Ya-Ping Tang
Found on Publication Page
37
Adult neurogenesis is functionally associated with AD-like neurodegeneration.. Qian Chen, Akira Nakajima, Se Hoon Choi, Xiaoli Xiong, Sangram S Sisodia, Ya-Ping Tang
Found on Publication Page
36
Expression of NR2B in Cerebellar Granule Cells Specifically Facilitates Effect of Motor Training on Motor Learning. Jianwei Jiao, Akira Nakajima, William G M Janssen, Vytautas P Bindokas, Xiaoli Xiong, John H Morrison, James R Brorson, Ya-Ping Tang
Found on Publication Page
35
Jiao J, Nakajima A, Janssen WG, Bindokas VP, Xiong X, Morrison JH, Brorson JR, Tang YP (2008) Expression of NR2B in cerebellar granule cells specifically facilitates effect of motor training on motor learning. PLoS ONE 3: e1684.
Found on Publication Text
In 2007
34
Maintenance of superior learning and memory function in NR2B transgenic mice during ageing. Xiaohua Cao, Zhenzhong Cui, Ruiben Feng, Ya-Ping Tang, Zhenxia Qin, Bing Mei, Joe Z Tsien
Found on Publication Page
In 2006
32
Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse.. Qian Chen, Akira Nakajima, Corbin Meacham, Ya-Ping Tang
Found on Publication Page
In 2005
31
Genetic approaches to the molecular/neuronal mechanisms underlying learning and memory in the mouse.. Akira Nakajima, Ya-Ping Tang
Found on Publication Page
30
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.. Orly Lazarov, John Robinson, Ya-Ping Tang, Ilana S Hairston, Zeljka Korade-Mirnics, Virginia M-Y Lee, Louis B Hersh, Robert M Sapolsky, Karoly Mirnics, Sangram S Sisodia
Found on Publication Page
In 2003
29
Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain.. Huimin Wang, Eiji Shimizu, Ya-Ping Tang, Min Cho, Maureen Kyin, Wenqi Zuo, Daphne A Robinson, Peter J Alaimo, Chao Zhang, Hiromi Morimoto, Min Zhuo, Ruiben Feng, Kevan M Shokat, Joe Z Tsien
Found on Publication Page
27
Wang H, Shimizu E, Tang YP, Cho M, Kyin M, Zuo W, Robinson DA, Alaimo PJ, Zhang C, Morimoto H, Zhuo M, Feng R, Shokat KM, Tsien JZ. (2003) Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain. Proc Natl Acad Sci USA 100: 4287-92.
Found on Publication Text
In 2002
26
Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces. Ruiben Feng, Claire Rampon, Y P Tang, David Shrom, Janice Jin, Maureen Kyin, Bryce Sopher, M W Miller, C B Ware, George M Martin, S H Kim, Ronald B Langdon, Sangram S Sisodia, Joe Z Tsien
Found on Publication Page
In 2001
25
Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex. Benjamin D. Philpot, Michael P. Weisberg, Margarita S. Ramos, Nathaniel B. Sawtell, Ya-Ping Tang, Joe Z. Tsien, Mark F. Bear
Found on Publication Page
24
Differential effects of enrichment on learning and memory function in NR2B transgenic mice.. Y P Tang, H Wang, R Feng, M Kyin, J Z Tsien
Found on Publication Page
23
Feng R, Rampon C, Tang YP, Shrom D, Jin J, Kyin M, Sopher, B, Miller MW, Ware CB, Martin GM, Kim SH, Langdon RB, Sisodia SS, Tsien JZ (2001) Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron 32: 911-26.
Found on Publication Text
22
Tang Y-P, Shimizu E, Tsien JZ (2001) Do 'smart' mice feel more pain, or are they just better learners? Nat Neurosci (comment) 4: 453-4.
Found on Publication Text
In 2000
21
Effects of environmental enrichment on gene expression in the brain.. C Rampon, C H Jiang, H Dong, Y P Tang, D J Lockhart, P G Schultz, J Z Tsien, Y Hu
Found on Publication Page
20
NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation.. E Shimizu, Y P Tang, C Rampon, J Z Tsien
Found on Publication Page
19
Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of -amyloid in rats. Ya-Ping Tang, Kiyofumi Yamada, Yasuhiko Kanou, Takashi Miyazaki, Xiao-Li Xiong, Fukushi Kambe, Yoshiharu Murata, Hisao Seo, Toshitaka Nabeshima
Found on Publication Page
18
Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice.. C Rampon, Y P Tang, J Goodhouse, E Shimizu, M Kyin, J Z Tsien
Found on Publication Page
17
Tang YP, Yamada K, Kanou Y, Miyazaki T, Xiong X, Kambe F, Murata Y, Seo H, Nabeshima T (2000) Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricularn infusion of beta-amyloid in rats. Brain Res Mol Brain Res 80: 188-97.
Found on Publication Text
In 1999
16
Genetic enhancement of learning and memory in mice. YP Tang, E Shimizu, G R Dube, C Rampon, GA Kerchner, M Zhuo, GS Liu, J Z Tsien
Found on Publication Page
15
Genetic enhancement of learning and memory in mice. Ya-Ping Tang, Eiji Shimizu, Gilles R. Dube, Claire Rampon, Geoffrey A. Kerchner, Min Zhuo, Guosong Liu, Joe Z. Tsien
Found on Publication Page
In 1998
14
Continuous infusion of -amyloid into the cerebral ventricle of rats promotes expression of BDNF messenger RNA in the hippocampus. Kiyofumi Yamada, Ya-Ping Tang, Yasuhiko Kano, Takashi Miyazaki, Yoshiharu Murata, Hisao Seo, Toshitaka Nabeshima
Found on Publication Page
In 1997
13
A concussive-like brain injury model in mice (I): impairment in learning and memory.. Y P Tang, Yukihiro Noda, Takaaki Hasegawa, Toshitaka Nabeshima
Found on Publication Page
12
A concussive-like brain injury model in mice (II): selective neuronal loss in the cortex and hippocampus.. Y P Tang, Yukihiro Noda, Takaaki Hasegawa, Toshitaka Nabeshima
Found on Publication Page
11
Effects of VA-045 on learning and memory deficits in traumatic brain injury (TBI)-induced retrograde and anterograde amnesic mice.. Y P Tang, Yukihiro Noda, Takaaki Hasegawa, Toshitaka Nabeshima
Found on Publication Page
10
Involvement of activation of dopaminergic neuronal system in learning and memory deficits associated with experimental mild traumatic brain injury.. Y P Tang, Yukihiro Noda, Toshitaka Nabeshima
Found on Publication Page
9
NGFI-B, c-fos, and c-jun mRNA Expression in Mouse Brain After Acute Carbon Monoxide Intoxication. Ya-Ping Tang, Yoshiharu Murata, Takashi Nagaya, Yukihiro Noda, Hisao Seo, Toshitaka Nabeshima
Found on Publication Page
8
(+)-Eburnamenine-14-carboxylic acid (2-nitroxyethyl) ester (VA-045), a putative cognitive enhancer, facilitates recovery from concussive brain injury-induced learning and memory impairments in mice. Ya-Ping Tang, Yukihiro Noda, Takaaki Hasegawa, Toshitaka Nabeshima
Found on Publication Page
7
A synergistic interaction between dopamine D1 and D2 receptor subtypes in the memory impairments induced by concussive brain injury (CBI) in mice.. Y P Tang, Y Noda, T Nabeshima
Found on Publication Page
Unspecified
6
Conditional protein knockout approach to synaptic erasure of old memories in mice. Eiji Shimizu, Ya-Ping Tang, Huimin Wang, Claire Rampon, Daphne A. Robinson, Anthony C. Bishop, Kevita Shah, Peter J. Alaimo, Hiromi Morimoto, Min Zhuo, Kevan M. Shokat, Joe Z. Tsien
Found on Publication Page
5
expression in the brain. Claire Rampon, Cecilia H. Jiang, Helin Dong, Ya-Ping Tang, David J. Lockhart, Peter G. Schultz, Joe Z. Tsien, Yinghe Hu
Found on Publication Page
4
Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces gles. These abnormal deposits accumulate in the brain. Ruiben Feng, Claire Rampon, Ya-Ping Tang, David Shrom, Janice Jin, Maureen Kyin, Bryce Sopher, George M. Martin, Seong-Hun Kim, Ronald B. Langdon, Sangram S. Sisodia, Joe Z. Tsien
Found on Publication Page
3
Joseph A, Chen Q, Tang M, Mamiya T, Jiao J, Gong B, Xiong X, Yu N, Yang LL, Xu TL, Zhuo M, Tang YP (2015?) Brain-derived neurotrophic factor (BDNF) is a gatekeeper for learning and memory. (Revision).
Found on Publication Text
2
Joseph A, Chen Q, Tang M, Mamiya T, Li X, Jiao J, Xiong X, Yu N, Luo Y, Tang YP (2015?) Brain-derived neurotrophic factor (BDNF) is a gatekeeper for behaviors in response to stress. (Revision).
Found on Publication Text
1
*, these authors contributed equally to this work.
Found on Publication Text
